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The full 5-year results of a long-term extension study of tildrakizumab for psoriasis show a high rate of sustained disease control coupled with a favorable safety profile during more than 5,400 patient-years of prospective follow-up, Diamont Thaçi, MD, PhD, reported at the virtual annual congress of the European Academy of Dermatology and Venereology. For example, 89% of
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Many of us are frittering away time on Facebook or Twitter as we hunker down at home during the pandemic. But there’s a potential upside to all this social media engagement: It lets public health officials know how people feel about Covid-19 restrictions and can be used to encourage compliance. Australian researchers found that social
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A novel algorithm-based disease management program, led by pharmacists and nonlicensed navigators, optimized cholesterol and blood pressure levels in high-risk patients, according to an interim report from the first 5000 patients. Mean low-density lipoprotein cholesterol (LDL-C) levels fell from 125 mg/dL to 73 mg/dL among those who finished active treatment titration and from 133 mg/dL
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Treatment with an investigational albumin-bound mTOR inhibitor showed long-lasting responses in patients with advanced malignant perivascular epithelioid cell tumors (PEComa), extended follow-up from the single-arm AMPECT study showed. On independent review, the overall response rate (ORR) with nab-sirolimus in 31 malignant PEComa patients was 39% (95% CI 22-58), including one complete response, meeting the primary
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The interventional cardiology community is mourning the loss of Prof Anthony “Tony” Gershlick, MBBS, who died November 20 of COVID-19. He was 69. Gershlick was a “talented, dedicated and much loved colleague,” reads a statement issued by the University of Leicester, where he was affiliated for more than three decades. Gershlick, a consultant cardiologist at
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Scientists involved in oversight of the Operation Warp Speed COVID-19 vaccine trials are tempering excitement about efficacy, noting that the studies haven’t shown yet whether the products can prevent transmission of the SARS-CoV-2 virus. “We don’t know if people can become
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Because of the stalled economy, especially reductions in air and auto traffic, US greenhouse gas emissions are expected to drop 9.2% in 2020, their lowest level in three decades, according to a study by BloombergNEF. Earlier studies have shown reductions in particulate matter, both here and abroad. That remarkable 9.2% drop is partially offset by
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The United States Medical Licensing Examination (USMLE) Step 2 Clinical Skills (CS) assessment is switching to a remote virtual format, according to an announcement detailed in a podcast on Thursday. The all-day exam, which traditionally requires test takers to have physical contact with standardized patients, has been suspended during the pandemic for safety reasons. Thursday’s
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Eight months after it began developing its Covid-19 vaccine, Pfizer formally filed for emergency use authorization from the US Food and Drug Administration on Friday. https://www.npr.org/2020/11/20/937026003/pfizer-asks-fda-to-approve-its-covid-19-vaccine-for-emergency-use “Filing for Emergency Use Authorization in the U.S. is a critical step in making our vaccine candidate available to the global population as quickly as possible,” BioNTech CEO Ugur
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We may have a new vaccine approved by the holidays. What we might not have is a clear picture of how to distribute it, according to President-elect Joe Biden’s transition team. Despite 11.5 million infected individuals and more than 250,000 US deaths from Covid-19 as of this morning, the Trump administration still refuses to allow
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The administrative burden of medicine significantly contributes to physician and clinician burnout, electronic health systems, or EHR system design and workflow as a lead culprit. As such, recent EHR technology innovation tactics have focused on automating components of data entry and documentation. These technology innovations could significantly reduce the amount of time we spend crafting
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The US Food and Drug Administration (FDA) today issued an emergency use authorization (EUA) for the janus kinase inhibitor baricitinib (Olumiant, Eli Lilly) in combination with remdesivir (Veklury, Gilead) for treating hospitalized adults and children at least 2 years old with suspected
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For sports lovers, the year 2020 is one to forget. Seasons have withstood many disruptions, only to be brought back in unfamiliar formats with few, if any, fans in the stands.  It’s also been a year to witness how well, or just the opposite, sports leagues have handled the pandemic. For some leagues, thanks to
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Health literacy is a global problem. Nine out of 10 adults have trouble applying the health information they see in the media or get from healthcare facilities to their own lives.  Defined as how well a person can find and understand the information they need, health literacy affects every decision we make about our health,
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Public health — the science of protecting and improving the health of a population — includes everything from setting pollution limits to urging women to get mammograms. It’s investigating salmonella outbreaks, tracking Lyme disease, defining drunk driving, fighting climate change, tackling
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Middle-age adults who took low-dose vitamin D supplements for 5 years had a small but statistically lower risk of developing metastatic or fatal cancer, a new analysis of a randomized trial showed. The absolute difference — 1.7% with vitamin D versus 2.1% without — represented a 17% reduction in relative risk (P=0.04). Normal-weight individuals derived
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The first guidelines for postoperative opioid prescribing for children and adolescents suggest considering alternatives to opioids for pain control and thinking in terms of stewardship when opioids are needed. Opioids are often prescribed for children and adolescents to alleviate postsurgical pain, but they may increase the risk for opioid use disorder or high-risk behavior, such
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“Dancing with the Stars” contestant Jeannie Mai has withdrawn from the show after she was admitted to the hospital with epiglottitis. Mai, a co-host on the afternoon talk show “The Real,” was shocked when what she thought was a simple sore throat was deemed to be a potentially life-threatening condition, and that she needed emergency
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Boston Scientific said it is voluntarily recalling all unused inventory of the Lotus Edge transcatheter aortic valve replacement system effective immediately. In making the announcement today, Boston Scientific chair and chief executive officer Mike Mahoney said the company has been increasingly challenged by the intricacies of the delivery system required to allow physicians to fully
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